Arsenic Trioxide is indicated for induction of remission and consolidation in patients with acute promyelocytic leukemia (APL) who are refractory to, or have relapsed from, retinoid and anthracycline chemotherapy. Mechanism of action. The mechanism of action of Arsenic Trioxide is not completely understood.
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Consolidation schedule. Arsenic Trioxide Phebra must be administered intravenously at a dose of 0.15 mg/kg/day, 5 days per week. Arsenic Trioxide is indicated for induction of remission and consolidation in patients with acute promyelocytic leukemia (APL) who are refractory to, or have relapsed from, retinoid and anthracycline chemotherapy. Mechanism of action. The mechanism of action of Arsenic Trioxide is not completely understood.
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MDL number MFCD00003433. eCl@ss 38080102 . PubChem Substance ID 24852110. NACRES NA.22 Arsenic Trioxide is formulated as a sterile, nonpyrogenic, clear solution of arsenic trioxide in water for injection using sodium hydroxide and dilute hydrochloric acid to adjust to pH 8.
ARSENIC TRIOXIDE, as As: METHOD 7901, Issue 2, dated 15 August 1994 - Page 3 of 4 6. Carefully rinse the material on the bottom of the watchglass, and the sides of the beaker into the sample solution with distilled water. Add 6 mL 30% H2O2. 7. Evaporate just to dryness on the steambath. 8. Cool beakers.
Elimination is rapid at first (half-life of 1–2 days), by methylation to monomethylarsonic acid and dimethylarsonic acid, and excretion in the urine, but a certain amount (30–40% in the case of repeated exposure) is incorporated into the bones, muscles, skin Arsenic trioxide Accord ges normalt av en läkare eller sjuksköterska, Det ges som ett dropp (en infusion) in i en ven under 1–2 timmar, men det kan ta längre tid om biverkning ar som hudrodnad och yrsel uppkommer. Arsenic trioxide Accord ska inte blandas med, eller ledas genom samma slang tillsammans med andra läkemedel.
Arsenic trioxide is approved to be used with tretinoin to treat: Acute promyelocytic leukemia (APL) in patients whose cancer has a certain type of chromosome mutation that affects the PML gene and RARA gene.
(235-727-4).
Arsenic(III)oxide.
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tell your doctor if you are breastfeeding. Your doctor will probably tell you not to breastfeed during your treatment and for 2 weeks after your final dose. you should know that this medication may decrease fertility in men.
Bara kunder som har loggat in kan beställa produkten. Multidrug-resistant neuroblastoma cells are responsive to arsenic trioxide at both normoxia and hypoxia.
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Long-term Safety Study of Arsenic Trioxide in Newly Diagnosed, Low-to-intermediate Risk Acute Promyelocytic Leukemia (APL0618) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators.
View information Synonym: Arsenic trioxide, Arsenous acid. Image of Arsenic(III) oxide. ARSENIC TRIOXIDE, ICSC: 0378.
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Arsenic trioxide Mylan är ett koncentrat till infusionsvätska, lösning (sterilt koncentrat). Arsenic trioxide Mylan tillhandahålls i glasflaskor i form av en koncentrerad, klar, färglös vattenlösning. Varje kartong innehåller 1 eller 10 glasflaskor för engångsbruk. Innehavare av godkännande för försäljning. Mylan Ireland Limited
Consolidation schedule. Arsenic Trioxide Phebra must be administered intravenously at a dose of 0.15 mg/kg/day, 5 days per week. Arsenic Trioxide is indicated for induction of remission and consolidation in patients with acute promyelocytic leukemia (APL) who are refractory to, or have relapsed from, retinoid and anthracycline chemotherapy.
Officiell transportbenämning. · ADR. 1561 ARSENIKTRIOXID. · IMDG, IATA. ARSENIC TRIOXIDE. · Faroklass för transport. · ADR. · Klass. 6.1 Giftiga ämnen.
23 Zhang et al. Arsenic Trioxide treated 72 cases of APL. Clin J Europeiska läkemedelsmyndighetens webbplats: Arsenic Trioxide Accord - EMA: EPAR PI finska svenska.
As an industrial chemical, major uses include in the manufacture of wood preservatives, pesticides, and glass. As a medication it is used to treat a type of cancer known as acute promyelocytic leukemia. Arsenic trioxide is used to treat a cancer of the blood and bone marrow called acute promyelocytic (pro-MYE-loe-SIT-ik) leukemia, or APL. Arsenic trioxide is sometimes given in combination with another medicine called tretinoin. Arsenic trioxide may also be used for other purposes not listed in this medication guide. Arsenic trioxide is approved to be used with tretinoin to treat: Acute promyelocytic leukemia (APL) in patients whose cancer has a certain type of chromosome mutation that affects the PML gene and RARA gene. Arsenic trioxide is immediately hydrolyzed to the active form, arsenious acid (As III) which is methylated (hepatically) to the less active pentavalent metabolites, monomethylarsonic acid (MMA v) and dimethylarsinic acid (DMA v) by methyltransferases; As III is also oxidized to the minor metabolite, arsenic acid (As v) Arsenic trioxide is the generic name for the trade name drug Trisenox®.